Cross Titration Formula:
From: | To: |
Antipsychotic cross-titration is the process of switching from one antipsychotic medication to another while maintaining therapeutic effect and minimizing side effects. This calculator provides approximate dose equivalents based on published conversion factors.
The calculator uses standard conversion factors:
Where conversion factors (relative to haloperidol 1mg):
Note: These are approximate values. Individual patient factors may require adjustment.
Details: Incorrect dose conversion can lead to breakthrough symptoms or excessive side effects. Cross-titration should typically be done gradually over days to weeks.
Instructions: Select current antipsychotic, enter current dose, select target antipsychotic. The calculator will provide the approximate equivalent dose.
Q1: Are these conversions exact?
A: No, these are approximate equivalents. Individual response varies based on metabolism, age, and other factors.
Q2: How quickly should I switch medications?
A: Typically over 1-4 weeks, gradually decreasing the old while increasing the new. Consult a psychiatrist.
Q3: What about depot injections?
A: Conversion factors differ for long-acting injectables. This calculator is for oral formulations.
Q4: Do these apply to children/elderly?
A: Elderly often require lower doses. Pediatric conversions may differ. Consult specialist guidelines.
Q5: What about clozapine?
A: Clozapine conversions are complex and not included here due to its unique properties.