1. What is Alligation?

Alligation is a mathematical method used in pharmacy to calculate the proportions of different strength solutions needed to produce a solution of intermediate strength. It's particularly useful for compounding medications.

2. How Alligation Works

The alligation method uses these formulas:

Explanation: The method determines the ratio of two solutions needed to achieve a desired concentration.

3. Pharmacy Applications

Details: Alligation is commonly used in pharmacy practice for preparing IV solutions, diluting concentrated medications, and compounding custom dosage forms.

4. Using the Calculator

Tips: Enter the higher and lower concentration percentages, the desired concentration (must be between the two), and the total quantity needed. All values must be positive numbers.

5. Frequently Asked Questions (FAQ)

Q1: When should I use alligation?
A: Use alligation when you need to mix two different strength solutions to obtain an intermediate strength.

Q2: Can alligation be used for solid mixtures?
A: Yes, the same principles apply when mixing powders or other solid dosage forms of different strengths.

Q3: What if my desired strength is outside the range?
A: The desired strength must be between your higher and lower strengths. If not, you'll need different starting materials.

Q4: How accurate is this method?
A: Alligation provides mathematically precise ratios, but actual preparation requires careful measurement and mixing.

Q5: Are there alternatives to alligation?
A: Yes, you could use the formula C1V1 = C2V2 for simple dilutions, but alligation is more efficient for mixing two strengths.