G5 Allele Frequency Formula:
From: | To: |
The G5 allele frequency represents the proportion of G5 alleles in a given population relative to all alleles at that locus. It's a fundamental measure in population genetics.
The calculator uses the allele frequency formula:
Where:
Explanation: The equation calculates the simple proportion of G5 alleles in the population sample.
Details: Allele frequencies are crucial for understanding genetic variation, population structure, and evolutionary processes. They help identify genetic markers associated with traits or diseases.
Tips: Enter the count of G5 alleles and the total number of alleles sampled. Both values must be non-negative integers, and total alleles must be greater than zero.
Q1: What does an allele frequency of 0 mean?
A: A frequency of 0 means the G5 allele was not observed in your sample, though it might exist at very low frequencies in the population.
Q2: What's considered a high allele frequency?
A: This depends on context. In general, frequencies above 0.05 (5%) are considered common variants, while lower frequencies represent rare variants.
Q3: How large should my sample be?
A: For accurate frequency estimates, larger samples (typically hundreds to thousands of individuals) are preferred to minimize sampling error.
Q4: Can frequency exceed 1?
A: No, allele frequencies range from 0 to 1, representing the proportion of that allele in the population.
Q5: How is this different from genotype frequency?
A: Allele frequency counts individual alleles, while genotype frequency counts combinations of alleles in individuals (e.g., homozygotes and heterozygotes).